JNCR

The mission of the journal is to contribute to the development of nursing science and care practices in Turkey and internationally. It is also to promote and disseminate new knowledge and research data for evidence-based care practices at all levels of nursing services. The Journal of Nursing Care Research deals with Fundamentals of Nursing, Internal Medicine Nursing, Surgical Nursing, Obstetrics and Gynecology Nursing, Child Health and Diseases Nursing, Mental Health and Diseases Nursing, Public Health Nursing and Management in Nursing and accepts articles on these topics.

Index
Original Article
Illness uncertainty as a determinant of self-efficacy among adults with chronic diseases
Aims: This study aimed to determine the relationship between illness uncertainty and self-efficacy levels among adults with chronic diseases.
Methods: This descriptive and cross-sectional study was conducted with 220 adult inpatients aged 18 years and older who were hospitalized in the Internal Medicine Department of a training and research hospital. Data were collected using the Patient Information Form, Mishel Uncertainty in Illness Scale (MUIS), and the 6-Item Self-Efficacy for Managing Chronic Disease Scale. Statistical analyses included descriptive statistics, correlation, and multiple regression tests, with a significance level of p<0.05.
Results: The mean age of the participants was 68.30±14.15 years; 51.4% were male, and 58.2% had a diagnosis of hypertension. The mean MUIS score was 48.80±12.98, and the mean self-efficacy score was 4.85±1.81. Regression analysis demonstrated a significant negative relationship between illness uncertainty and self-efficacy (ß = -0.467, p < 0.001), explaining 21.4% of the variance (Adjusted R² = 0.214, p < 0.001). In the extended model, lower education and income levels, higher hospitalization frequency, comorbidities, polypharmacy, and higher MUIS scores negatively predicted self-efficacy, while employment, smoking cessation, longer disease duration, and regular medical follow-up were positive predictors. The final model explained 62.9% of the variance (Adjusted R² = 0.629, p < 0.001).
Conclusion: As illness uncertainty increases, self-efficacy decreases among adults with chronic diseases. These findings emphasize the importance of nursing interventions aimed at reducing uncertainty, enhancing self-efficacy, and supporting effective chronic disease management.


Ali, M. M. M., Çelik, S., Er, S., & Anataca, G. (2025). Bridging illness uncertainty and self-care: the role of cognitive emotion regulation in type 2 diabetes management. Prim Care Diabetes, 19(4), 375-382. doi:10.1016/ j.pcd.2025.04.001
Arslan, B. (2024). İç hastalıkları hemşirelerinin sık karşılaştığı bir gerçek; “belirsizlik” kavramına kuramsal bakış. Hitit Sağlık Dergisi, (2), 40-54.
Bahar, G., Savaş, H. A., Ünal, A., Savaş, E., Kaya, H., & Bahar, A. (2014). Morisky Tedavi Uyum Ölçeğinin iki uçlu duygudurum bozukluğu için geçerlilik ve güvenilirlik çalışması. Anadolu Psikiyatri Dergisi, 15(2), 141-149.
Bakan, G., & İnci, F. H. (2021). Predictor of self-efficacy in individuals with chronic disease: stress-coping strategies. J Clin Nurs, 30(5-6), 874-881. doi:10.1111/jocn.15633
Brown, A., Hayden, S., Klingman, K., & Hussey, L. C. (2020). Managing uncertainty in chronic illness from patient perspectives. J Excellence Nurs Healthcare Pract, 2(1), 1. doi:10.5590/JENHP.2020.2.1.01
Cal, A., & Aydin Avci, I. (2021). Turkish adaptation of the Mishel uncertainty in illness scale-community form. Perspect Psychiatr Care, 57(4), 2006-2013. doi:10.1111/ppc.12874
Ceyhan, Y. Ş., & Ünsal, A. (2018). Farklı kronik hastalığı olan bireylerin öz-etkililik düzeylerinin karşılaştırılması. DEUHFED, 11(4), 263-273.
Çınar, D., Yıldırım, Y., & Aykar, F. Ş. (2020). Kanser tanılı hastanın Merley Mishel’in hastalıkta belirsizlik kuramına göre hemşirelik bakımı. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 11(3), 553-559. doi:10. 31067/0.2020.306
Demirbaş, N., & Kutlu, R. (2020). Çoklu ilaç kullanan yetişkin bireylerin tedaviye uyumu ve öz-etkililik düzeyleri. Ankara Medical Journal, 20(2), 269-280. doi:10.5505/amj.2020.16362
Dünya, C. P., Çelik, M., & Çelik, S. (2025). Kronik hastalığa sahip bireylerde hastalığa uyum, ilaç uyumu, acil servis ziyaret sıklığı ve yaşam kalitesi arasındaki ilişki. Med J West Black Sea, 9(1), 68-75. doi:10.29058/mjwbs.1503892
Farley, H. (2020). Promoting self-efficacy in patients with chronic disease beyond traditional education: a literature review. Nursing Open, 7(1), 30-41. doi:10.1002/nop2.382
Güney, A., & Basit, G. (2023). Relationship between disease adaptation and self-efficacy for disease management in individuals with multiple chronic diseases. Gevher Nesibe J Med& Health Sci, 8(4), 1191-1201. doi: 10.5281/zenodo.10049232
Hwang, M. K., Kim, H. K., & Lee, K. H. (2023). Effects of uncertainty, appraisal of uncertainty, and self-efficacy on the quality of life of elderly patients with lung cancer receiving chemotherapy: based on Mishel’s theory of uncertainty. Medicina (Kaunas), 59(6), 1051. doi:10.3390/medicina59061051
İncirkuş, K. (2024). Uyku kalitesi ve kronik hastalık yönetimi için öz-etkililik: Edirne ilindeki yaşlı popülasyonu üzerine kesitsel bir çalışma. Turkish J Family Med Primary Care, 18(2), 126-132. doi:10.21763/tjfmpc. 1387989
İncirkuş, K., & Nahcivan, N. (2020). Validity and reliability study of the Turkish version of the self-efficacy for managing chronic disease 6-item scale. Turkish J Med Sci, 50(5), 1254-1261. doi:10.3906/sag-1910-13
Kaynak, G. K. (2022). Kronik hastalıklarda öz yeterlilik algısı: Türkiye’de gerçekleştirilen çalışmalar üzerine bir derleme. Oltu Beşeri ve Sosyal Bilimler Fakültesi Dergisi, 3(2), 79-86. doi:10.5152/OJFHSS.2022.22714
Kuijer, R. G., & De Ridder, D. T. (2003). Discrepancy in illness-related goals and quality of life in chronically ill patients: the role of self-efficacy. Psychology & Health, 18(3), 313-330. doi:10.1080/0887044031000146815
Lorig, K. R., Sobel, D. S., Ritter, P. L., Laurent, D., & Hobbs, M. (2001). Effect of a self-management program on patients with chronic disease. Eff Clin Pract, 4(6), 256-262.
Mishel, M. H. (1988). Uncertainty in illness. Image: The Journal of Nursing Scholarship, 20(4), 225-232. doi:10.1111/j.1547-5069.1988.tb00082.x
Mishel, M. H., & Epstein, D. (1997). Uncertainty in illness scales manual (pp. 4-9). University of North Carolina.
Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care, 24(1), 67-74.
Shakya, D. (2018). Self-efficacy among patients with chronic diseases and its associated factors. J Kathmandu Med College, 7(3), 82-88.
Skojec, T. A., Davidson, T. M., & Kelechi, T. J. (2025). The relationship between uncertainty in illness and psychological adjustment to chronic illness. J Health Psychol, 30(4), 622-637. doi:10.1177/13591053241249861
Uğuz, Ö., & Doğan, S. (2025). Relationship between posttraumatic growth and illness uncertainty in young women with breast cancer: the mediating role of self-compassion. Cancer Nursing. Advance online publication. doi:10.1097/NCC.0000000000001434
Verduzco-Aguirre, H. C., Babu, D., Mohile, S. G., Bautista, J., Xu, H., Culakova, E., ... & Loh, K. P. (2021). Associations of uncertainty with psychological health and quality of life in older adults with advanced cancer. J Pain Symptom Management, 61(2), 369-376. doi:10.1016/j.jpainsymman.2020.08.012
World Health Organization. (2025, September 25). Noncommunicable diseases [Fact sheet]. Retrieved October 17, 2025, from https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases
Zhang, Y., Kwekkeboom, K., & Petrini, M. (2015). Uncertainty, self-efficacy, and self-care behavior in patients with breast cancer undergoing chemotherapy in China. Cancer Nursing, 38(3), E19-E26. doi:10.1097/NCC.0000000000000165
Volume 2, Issue 4, 2025
Page : 112-118
_Footer